{"id":7274,"date":"2024-04-11T06:27:34","date_gmt":"2024-04-11T06:27:34","guid":{"rendered":"https:\/\/staging5.iclickwebdesign.sg\/nscc\/?post_type=portfolio&#038;p=7274"},"modified":"2024-07-11T03:01:54","modified_gmt":"2024-07-11T03:01:54","slug":"mapping-the-evolution-of-the-500-million-year-old-horseshoe-crab","status":"publish","type":"portfolio","link":"https:\/\/www-7171.nscc.sg\/portfolio\/item\/mapping-the-evolution-of-the-500-million-year-old-horseshoe-crab\/","title":{"rendered":"Mapping the evolution of the 500 million year-old horseshoe crab"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"7274\" class=\"elementor elementor-7274\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-22db4b3 elementor-section-full_width elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"22db4b3\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9ca7cb7\" data-id=\"9ca7cb7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ec64d8a elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ec64d8a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-aac7d1b\" data-id=\"aac7d1b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ed72f75 elementor-widget elementor-widget-itsulu-intro\" data-id=\"ed72f75\" data-element_type=\"widget\" data-widget_type=\"itsulu-intro.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t<!-- banner -->\n\t\t<div class=\"mil-banner-sm\">\n\t\t\t\t\t\t<div class=\"mil-banner-content\">\n\t\t\t\t\t\t\t\t<div class=\"mil-breadcrumbs mil-mb-30 mil-light\">\n\t\t\t\t\t<ul><li><a href=\"https:\/\/www-7171.nscc.sg\" title=\"NSCC\"><span>NSCC Singapore<\/span><\/a><\/li><li class=\"current\"><span><\/span><\/li><\/ul>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<h1 class=\"mil-h2 mil-uppercase mil-light\">\n\t\t\t\t\t<span >\n\t\t\t\t\t\tMapping the evolution of the 500 million year-old horseshoe crab\t\t\t\t\t<\/span>\n\t\t\t\t<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-suptitle mil-accent mil-light\">\n\t\t\t\t\t<span >\n\t\t\t\t\t\tThe genomic study of the horseshoe crab, which was done using NSCC\u2019s supercomputing resources, can help in the conservation of the horseshoe crab and decipher its remarkably sensitive immune system.\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t<!-- banner end -->\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-daf0b91 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"daf0b91\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c4a8aa7\" data-id=\"c4a8aa7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-61161cf elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"61161cf\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-6d913d9\" data-id=\"6d913d9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-25fcf2d elementor-widget elementor-widget-text-editor\" data-id=\"25fcf2d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>The horseshoe crab has remained relatively unchanged after nearly half a billion years of evolutionary history. New genomic research led by scientists from A*STAR\u2019s Institute of Molecular and Cell Biology (IMCB), with help from NUS and Republic Polytechnic researchers, have generated the most contiguous high-quality, chromosome-scale genome assembly for the mangrove horseshoe crab to date. The study was recently published in the journal Nature Communications. The genomics study is a valuable resource for the conservation of this endangered species and is an important component in providing greater insight about the innate immune system of horseshoe crabs. A protein found in the blood of horseshoe crabs is used in the pharmaceutical and medical industry as an extremely sensitive agent for detecting endotoxin contamination.<\/p><p>\u00a0<\/p><p>\u201cAn important prerequisite for formulating effective conservation strategies is an understanding of genetic diversity and population structure but at present, there is no information about the population genetics of horseshoe crabs in Singapore,\u201d said Professor Byrappa Venkatesh, who is the Research Director that heads the Comparative and Medical Genomics Laboratory at IMCB. Analysis of this highly-contiguous genome has revealed novel information about the evolution of the horseshoe crab including the possibility that there have been three rounds of whole-genome duplication in its lineage.<\/p><p>\u00a0<\/p><p>\u201cOur study has shown that there was a marked decline in the population size of the mangrove horseshoe crab approximately 60,000 years ago coinciding with the onset of the recent ice age which has failed to recover due to the recent increased human activities such as the modification of coastal areas and overexploitation. Some suggestions for managing horseshoe crab stocks are habitat conservation, prohibiting horseshoe crab harvest, and protection of their breeding grounds,\u201d added Professor Venkatesh. Analysis of the mangrove horseshoe crab genome has identified many tandem gene clusters that are specific to its lineage including those that play important roles in the horseshoe crab\u2019s innate immunity. For the horseshoe crabs to survive and propagate successfully in a mangrove environment where they are exposed to a variety of pathogens, they have evolved a sophisticated immune system response network for recognising, immobilising and killing of pathogens.<\/p><p>\u00a0<\/p><p>\u201cThe horseshoe crabs\u2019 amebocytes are extremely sensitive to bacteria and hence is routinely used as a sensitive agent for detecting bacterial endotoxin,\u201d explained Professor Venkatesh. \u201cThe expanded immune system gene families identified in our study are likely to be important components of the horseshoe crab\u2019s immune response network which helps them mount a rapid and effective immune response to counteract pathogens.\u201d<\/p><p>\u00a0<\/p><p>To achieve the chromosome-scale genome assembly study, Professor Venkatesh and his team leveraged NSCC\u2019s high performance computing resources. \u201cOur genome project used state-of-the-art \u2018third-generation sequencing\u2019 technology which involves single-molecule real time sequencing (SMRT) that generates reads of 20,000 base pairs (bp) and longer, which are necessary to provide the highest contiguity to the genome,\u201d said Professor Venkatesh adding that the horseshoe crab genome is relatively large (approximately 2 Gb) and the team generated SMRT reads amounting to 100 times the size of the genome (200 Gb).<\/p><p>\u00a0<\/p><p>\u201cThe only way we could assemble the genome was by using the large number of high-performance nodes of the NSCC as conventional computational systems are incapable of assembling such a large amount of long reads. This allowed us to assemble the genome in a reasonable period and attempt several combinations of parameters to generate alternate assemblies that enabled us to obtain the best possible final genome assembly.\u201d<\/p><p>\u00a0<\/p><p>For more information about the study, please refer to the paper entitled, \u201c<a class=\"mil-accent\" href=\"https:\/\/www.nature.com\/articles\/s41467-020-16180-1\" target=\"_blank\" rel=\"noopener\">Chromosome-level assembly of the horseshoe crab genome provides insights into its genome evolution<\/a>\u201d.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7bc4da2 elementor-widget elementor-widget-text-editor\" data-id=\"7bc4da2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>To find out more about how NSCC\u2019s HPC resources can help you, please contact\u00a0<a class=\"mil-accent\" href=\"mailto:e-news@nscc.sg\">e-news@nscc.sg<\/a>.<\/p><p>\u00a0<\/p><p style=\"text-align: left;\">NSCC NewsBytes <a class=\"mil-accent\" href=\"https:\/\/www.nscc.sg\/wp-content\/uploads\/2020\/08\/NewsBytesFULL-June-2020-issueFinal.pdf\">June 2020<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e1f7764 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e1f7764\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c2d9e62\" data-id=\"c2d9e62\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2228a96 elementor-widget elementor-widget-itsulu-button\" data-id=\"2228a96\" data-element_type=\"widget\" data-widget_type=\"itsulu-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t\t\t<!-- Button -->\n\t\t<a class=\"mil-link\" href=\"\/nscc\/case-studies\/\">\n\t\t\t\t\t\t<span >\n\t\t\t\tBack To Case Studies\t\t\t<\/span>\n\t\t\t<i class=\"fas fa-arrow-right\"><\/i>\t\t\t    \t<\/a>\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e7f64ca elementor-widget elementor-widget-spacer\" data-id=\"e7f64ca\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c9c0f27 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"c9c0f27\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7fd8922\" data-id=\"7fd8922\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-dd6ce82 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"dd6ce82\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-2e9c877\" data-id=\"2e9c877\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d543c4d elementor-widget elementor-widget-heading\" data-id=\"d543c4d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\"><span class=\"mil-accent\">Other<\/span> Case Studies<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-f0e21bb elementor-widget elementor-widget-itsulu-portfolio-carousel\" data-id=\"f0e21bb\" data-element_type=\"widget\" data-widget_type=\"itsulu-portfolio-carousel.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t\t\t<div class=\"swiper-container mil-events-slider\" data-autoplay=\"6000\">\n\t\t\t<div class=\"mil-adaptive-right\">\n\t\t\t\t<div class=\"mil-slider-nav\">\n\t\t\t\t\t<div class=\"mil-slider-btn-prev mil-events-prev\"><i class=\"fas fa-arrow-left\"><\/i><span class=\"mil-h6\">Prev<\/span><\/div>\n\t\t\t\t\t<div class=\"mil-slider-btn-next mil-events-next\"><span class=\"mil-h6\">Next<\/span><i class=\"fas fa-arrow-right\"><\/i><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"swiper-wrapper\">\n\t\t\t\t\t\t\t\t\t\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/taking-a-stratified-approach-to-the-prevention-of-type-2-diabetes-in-the-asian-population\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/08\/Untitled-design-4-1200x675.jpg\" alt=\"Taking a stratified approach to the prevention of Type 2 diabetes in the Asian population\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Health and Biomedical Sciences<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tTaking a stratified approach to the prevention of Type 2 diabetes in the Asian population\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p><strong><em>Researchers from Nanyang Technological University (NTU) and their collaborators are investigating the molecular regulatory disturbances underlying development of Type 2 diabetes amongst Asian populations.<\/em><\/strong><\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/when-is-water-not-just-water\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Credit-NTU-1.png\" alt=\"When is water not just water?\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Urban Solutions and Sustainability<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tWhen is water not just water?\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>NSCC\u2019s supercomputing resource is helping researchers gain a better understanding of the true nature of water, and its properties. Although it is one of the most common elements,&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/balancing-skin-bacterial-composition-for-healthier-skin\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Untitled-design-39.png\" alt=\"Balancing skin bacterial composition for healthier skin\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Health and Biomedical Sciences<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tBalancing skin bacterial composition for healthier skin\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>NSCC\u2019s supercomputer help analyse the Asian skin microbiome in order to develop products to improve skin treatments and maintain skin health. Our skin harbours a complex&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/speeding-up-the-process-of-materials-discovery-and-development-using-hpc\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Material-discovery.png\" alt=\"Speeding up the process of materials discovery and development using HPC\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Advanced Manufacturing and Engineering<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tSpeeding up the process of materials discovery and development using HPC\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>NSCC\u2019s supercomputer helps perform high-throughput computations to accelerate the process of alloy development and to make it more cost effective. Traditional pathways in the&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/urban-planning-simulation-tool-based-on-hpc-technology-wins-presidents-technology-award-pta\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Urban-planning.png\" alt=\"Urban planning simulation tool based on HPC technology wins President\u2019s Technology Award (PTA)\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Urban Solutions and Sustainability<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tUrban planning simulation tool based on HPC technology wins President\u2019s Technology Award (PTA)\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>Using the ASPIRE 1 supercomputer, the tool was used to create a complete three-dimensional (3D) air flow simulation encompassing Singapore\u2019s built environment. A research team&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/monitoring-the-health-of-trees-with-supercomputer-enabled-deep-learning-tools\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Untitled-design-21.png\" alt=\"Monitoring the health of trees with supercomputer-enabled deep learning tools\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Urban Solutions and Sustainability<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tMonitoring the health of trees with supercomputer-enabled deep learning tools\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>Researchers from NTU leverage high-performance computing to develop tools to assess tree health in order to prevent tree falls. For Singapore\u2019s thriving, lush greenery, the&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":7158,"menu_order":0,"template":"template-elementor-default.php","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"portfolio_categories":[21],"class_list":["post-7274","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio\/7274"}],"collection":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/types\/portfolio"}],"version-history":[{"count":26,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio\/7274\/revisions"}],"predecessor-version":[{"id":14088,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio\/7274\/revisions\/14088"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/media\/7158"}],"wp:attachment":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/media?parent=7274"}],"wp:term":[{"taxonomy":"portfolio_categories","embeddable":true,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio_categories?post=7274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}