{"id":6098,"date":"2024-04-05T09:58:51","date_gmt":"2024-04-05T09:58:51","guid":{"rendered":"https:\/\/staging5.iclickwebdesign.sg\/nscc\/?post_type=portfolio&#038;p=6098"},"modified":"2024-07-11T03:16:36","modified_gmt":"2024-07-11T03:16:36","slug":"tackling-antibiotic-resistance-with-hpc","status":"publish","type":"portfolio","link":"https:\/\/www-7171.nscc.sg\/portfolio\/item\/tackling-antibiotic-resistance-with-hpc\/","title":{"rendered":"Tackling antibiotic resistance with HPC"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"6098\" class=\"elementor elementor-6098\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3c2ad25 elementor-section-full_width elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"3c2ad25\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-86a51f6\" data-id=\"86a51f6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ff44448 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ff44448\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5146465\" data-id=\"5146465\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-09ab1b4 elementor-widget elementor-widget-itsulu-intro\" data-id=\"09ab1b4\" data-element_type=\"widget\" data-widget_type=\"itsulu-intro.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t<!-- banner -->\n\t\t<div class=\"mil-banner-sm\">\n\t\t\t\t\t\t<div class=\"mil-banner-content\">\n\t\t\t\t\t\t\t\t<div class=\"mil-breadcrumbs mil-mb-30 mil-light\">\n\t\t\t\t\t<ul><li><a href=\"https:\/\/www-7171.nscc.sg\" title=\"NSCC\"><span>NSCC Singapore<\/span><\/a><\/li><li class=\"current\"><span><\/span><\/li><\/ul>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<h1 class=\"mil-h2 mil-uppercase mil-light\">\n\t\t\t\t\t<span >\n\t\t\t\t\t\tTackling antibiotic resistance with HPC\t\t\t\t\t<\/span>\n\t\t\t\t<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-suptitle mil-accent mil-light\">\n\t\t\t\t\t<span >\n\t\t\t\t\t\tTackling antibiotic resistance with HPC\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t<!-- banner end -->\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-daf0b91 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"daf0b91\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c4a8aa7\" data-id=\"c4a8aa7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-61161cf elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"61161cf\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-6d913d9\" data-id=\"6d913d9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-25fcf2d elementor-widget elementor-widget-text-editor\" data-id=\"25fcf2d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Antimicrobial resistance (AMR) is a global healthcare issue, which has resulted in 1.27 million deaths in 2019 and is expected to cause 10 million deaths by 2050. The excessive use of antibiotics is often cited as the major contributing factor for the evolution of bacterial resistance. Traditional antibiotics often fail in the treatment of multi-drug resistant (MDR) bacterial infections as they interfere with biosynthetic pathways that can easily be circumvented by the bacteria through mutation.<\/p><p>\u00a0<\/p><p>Membrane-active antimicrobials such as synthetic mimics of antimicrobial peptides (SMAMPs), is a potential solution to this problem as these molecules interfere with membrane function, an essential component of bacterial survival. However, the development of SMAMPs is largely by trial and error and little is known about how the membrane should be designed to target molecules due to the lack of molecular principles and poor understanding of the action mechanism.<\/p><p>\u00a0<\/p><p>A research team at\u00a0<a class=\"mil-accent\" href=\"https:\/\/www.a-star.edu.sg\/bii\">A*STAR Bioinformatics Institute (BII)<\/a>\u00a0is tapping on NSCC\u2019s supercomputing resources to employ a multi-disciplinary approach that involves in silico simulations and experimental validations to accelerate the development of membrane targeting antimicrobials. For example, based on the atomistic insights obtained from in silico simulations, the team has developed a pharmacophore model for the design of new antimicrobials targeting the bacterial membrane (Figure 1), which greatly accelerated the development of new antibiotics. One of the in silico designed compound displayed excellent antimicrobial activity and has been patented for further development.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0b8bba elementor-widget elementor-widget-image\" data-id=\"c0b8bba\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"900\" height=\"446\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1.png\" class=\"attachment-large size-large wp-image-6216\" alt=\"\" srcset=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1.png 1024w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-300x149.png 300w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-100x50.png 100w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-768x380.png 768w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-200x99.png 200w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-400x198.png 400w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-800x396.png 800w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Fig-1-1-1024x507-1-1000x495.png 1000w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f94ecb elementor-widget elementor-widget-itsulu-divider\" data-id=\"5f94ecb\" data-element_type=\"widget\" data-widget_type=\"itsulu-divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t<div class=\"mil-divider\"><\/div>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e1f7764 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e1f7764\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c2d9e62\" data-id=\"c2d9e62\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-adc66de elementor-hidden-mobile elementor-widget elementor-widget-text-editor\" data-id=\"adc66de\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><img decoding=\"async\" class=\"size-full wp-image-6219 alignleft\" src=\"https:\/\/ncss.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1.png\" alt=\"\" width=\"300\" height=\"278\" srcset=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1.png 300w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1-100x93.png 100w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1-200x185.png 200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p><p>New analogues will be designed based on the atomistic insights from the simulations. The translation of in silico insights to practical antibiotic development will greatly accelerate the drug discovery process, providing cost saving measures, as well as the basis for a continued developmental process to meet new challenges presented by pathogens.<\/p><p>\u00a0<\/p><p>To find out more about how NSCC\u2019s HPC resources can help you, please contact\u00a0<a class=\"mil-accent\" href=\"mailto:e-news@nscc.sg\">e-news@nscc.sg<\/a>.<\/p><p>\u00a0<\/p><section class=\"case-studies-info\"><p style=\"text-align: left;\">NSCC NewsBytes <a class=\"mil-accent\" href=\"https:\/\/www.nscc.sg\/wp-content\/uploads\/2023\/07\/NewsBytes_Jul2023-1.pdf\">July 2023<\/a><\/p><\/section>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-135c7c3 elementor-hidden-desktop elementor-hidden-tablet elementor-widget elementor-widget-text-editor\" data-id=\"135c7c3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><img decoding=\"async\" class=\"wp-image-6219 size-full aligncenter\" src=\"https:\/\/ncss.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1.png\" alt=\"\" width=\"300\" height=\"278\" srcset=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1.png 300w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1-100x93.png 100w, https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Dr-Li-Jianguo-300x278-1-200x185.png 200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p><p>New analogues will be designed based on the atomistic insights from the simulations. The translation of in silico insights to practical antibiotic development will greatly accelerate the drug discovery process, providing cost saving measures, as well as the basis for a continued developmental process to meet new challenges presented by pathogens.<\/p><p>\u00a0<\/p><p>To find out more about how NSCC\u2019s HPC resources can help you, please contact\u00a0<a class=\"mil-accent\" href=\"mailto:e-news@nscc.sg\">e-news@nscc.sg<\/a>.<\/p><p>\u00a0<\/p><section class=\"case-studies-info\"><p style=\"text-align: left;\">NSCC NewsBytes <a class=\"mil-accent\" href=\"https:\/\/www.nscc.sg\/wp-content\/uploads\/2023\/07\/NewsBytes_Jul2023-1.pdf\">July 2023<\/a><\/p><\/section>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2228a96 elementor-widget elementor-widget-itsulu-button\" data-id=\"2228a96\" data-element_type=\"widget\" data-widget_type=\"itsulu-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t\t\t<!-- Button -->\n\t\t<a class=\"mil-link\" href=\"\/nscc\/case-studies\/\">\n\t\t\t\t\t\t<span >\n\t\t\t\tBack To Case Studies\t\t\t<\/span>\n\t\t\t<i class=\"fas fa-arrow-right\"><\/i>\t\t\t    \t<\/a>\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e7f64ca elementor-widget elementor-widget-spacer\" data-id=\"e7f64ca\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c9c0f27 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"c9c0f27\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7fd8922\" data-id=\"7fd8922\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-dd6ce82 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"dd6ce82\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-2e9c877\" data-id=\"2e9c877\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d543c4d elementor-widget elementor-widget-heading\" data-id=\"d543c4d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\"><span class=\"mil-accent\">Other<\/span> Case Studies<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-f0e21bb elementor-widget elementor-widget-itsulu-portfolio-carousel\" data-id=\"f0e21bb\" data-element_type=\"widget\" data-widget_type=\"itsulu-portfolio-carousel.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\n\t\t\t\t<div class=\"swiper-container mil-events-slider\" data-autoplay=\"6000\">\n\t\t\t<div class=\"mil-adaptive-right\">\n\t\t\t\t<div class=\"mil-slider-nav\">\n\t\t\t\t\t<div class=\"mil-slider-btn-prev mil-events-prev\"><i class=\"fas fa-arrow-left\"><\/i><span class=\"mil-h6\">Prev<\/span><\/div>\n\t\t\t\t\t<div class=\"mil-slider-btn-next mil-events-next\"><span class=\"mil-h6\">Next<\/span><i class=\"fas fa-arrow-right\"><\/i><\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"swiper-wrapper\">\n\t\t\t\t\t\t\t\t\t\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/high-performance-computing-for-studying-and-preserving-marine-ecosystems\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Untitled-design-67.png\" alt=\"High performance computing for studying and preserving marine ecosystems\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Urban Solutions and Sustainability<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tHigh performance computing for studying and preserving marine ecosystems\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>The Reef Ecology Lab at NUS leverages NSCC\u2019s supercomputing capabilities for marine genomic analyses to better understand and design solutions for marine conservation in&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/enhancing-oil-recovery-techniques-for-the-oil-and-gas-industry\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Enhancing-Oil-Recovery-Techniques-For-The-Oil-And-Gas-Industry.png\" alt=\"Enhancing oil recovery techniques for the oil and gas industry\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Health and Biomedical Sciences<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tEnhancing oil recovery techniques for the oil and gas industry\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>Developing advanced functional polymer particles for enhanced flow assurance through the use of NSCC\u2019s supercomputing resources. Around 60% of oil deposits remain unrecovered in&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/improving-singapores-food-security\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Kale_diversity1.png\" alt=\"Improving Singapore\u2019s Food Security\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Urban Solutions and Sustainability<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tImproving Singapore\u2019s Food Security\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>Researchers from the National University of Singapore are creating indoor-adapted crops to increase Singapore\u2019s food production, with the help of NSCC Singapore\u2019s HPC&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/accelerating-the-discovery-of-new-2d-materials-using-hpc\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/Discovery-of-2D-materials-using-HPC.png\" alt=\"Accelerating the discovery of new 2D materials using HPC\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Advanced Manufacturing and Engineering<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tAccelerating the discovery of new 2D materials using HPC\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>New 2D materials are being discovered every day. At the NUS Centre for Advanced 2D Materials (CA2DM), researchers have been building up a database of 6,000 candidate 2D&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/privacy-preserving-data-fusion-for-traffic-state-estimation\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/08\/Untitled-design-3-1200x675.jpg\" alt=\"Privacy-Preserving Data Fusion for Traffic State Estimation\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Urban Solutions and Sustainability<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tPrivacy-Preserving Data Fusion for Traffic State Estimation\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p><strong>Researchers from NUS are proposing a privacy-preserved data fusion algorithm for traffic state estimation (FedTSE) to facilitate collaboration and data sharing between multiple data owners&#8230;<\/strong><\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\n\n<div class=\"swiper-slide\">\n\t<a href=\"https:\/\/www-7171.nscc.sg\/portfolio\/item\/supercomputer-sequences-genome-of-singapores-multi-ethnic-asian-population\/\" class=\"mil-card-2\">\n\t\t\t\t<div class=\"mil-cover-frame\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/www-7171.nscc.sg\/wp-content\/uploads\/2024\/04\/case-studies_6.jpg\" alt=\"Supercomputer sequences genome of Singapore\u2019s multi-ethnic Asian population\" \/>\n\t\t<\/div>\n\t\t\t\t<div class=\"mil-description\">\n\t\t\t<div class=\"mil-card-title\">\n\t\t\t\t\t\t\t\t<div class=\"mil-h6 mil-accent mil-mb-10\">\n\t\t\t\t\t<span>Health and Biomedical Sciences<\/span>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mil-h4 mil-mb-15\">\n\t\t\t\t\tSupercomputer sequences genome of Singapore\u2019s multi-ethnic Asian population\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"mil-card-text\">\n\t\t\t\t<div>\n\t\t\t\t\t<p>The analysis of this genetic data helps researchers expand the understanding of the biology of diseases that affect Singaporeans.   A new study \u2013 said to be the largest&#8230;<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/a>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":6191,"menu_order":0,"template":"template-elementor-default.php","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"portfolio_categories":[21],"class_list":["post-6098","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio\/6098"}],"collection":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/types\/portfolio"}],"version-history":[{"count":32,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio\/6098\/revisions"}],"predecessor-version":[{"id":14148,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio\/6098\/revisions\/14148"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/media\/6191"}],"wp:attachment":[{"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/media?parent=6098"}],"wp:term":[{"taxonomy":"portfolio_categories","embeddable":true,"href":"https:\/\/www-7171.nscc.sg\/wp-json\/wp\/v2\/portfolio_categories?post=6098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}